Okokuqala, ukwakheka kwayo kuhlangene, kuncane ngosayizi, kulula ukuyifaka nokuyigcina. Okwesibili, i-valve yebhola inomklamo ogcwele umnyango ovumela ukugeleza kugeleza ngaphandle kokuvinjelwa, ukunciphisa ukulahlekelwa kwengcindezi nokuthuthukisa ukusebenza kahle kwesistimu yonke. Okwesithathu, isebenzisa umklamo wokuvikela umlilo kanye nezinto ezingakwazi ukumelana nokushisa okuphezulu kanye nezindawo zokucindezela okukhulu, ukuqinisekisa ukuphepha kwesistimu. Ngaphezu kwalokho, ukusebenza kokuvala ama-valve ebhola lensimbi yegesi kuhle, kungagwema ngokuphumelelayo ukuvuza nokuvuza kwegesi, futhi kuqinisekise ukwethembeka nokuphepha kokusebenza.

Ngaphezu kwezici nemisebenzi engenhla, i-valve yebhola yegesi nayo inezinzuzo ezilandelayo. Okokuqala, ama-valve ebhola alula ukusebenza futhi aguquguqukayo, adinga kuphela ukujikeleza kwama-degree angu-90 ekushintsheni ukusebenza, futhi i-matrix yokuvala incane, iyonga futhi ilula. Okwesibili, impilo ye-Ball Valve yinde, impilo yesevisi ingaba ngamashumi ezinkulungwane zemijikelezo evulekile, akulula ukugqoka, ukunciphisa imvamisa kanye nezindleko zokushintshwa nokugcinwa.

Ukwelashwa kwe-Surface electrophoresis, ukuthungwa okubushelelezi, ukuphrinta kucacile kakhulu, izinga eliphezulu.